Gene therapy for arthritis -- Gene therapy for the treatment of inflammatory bowel disease -- Gene therapy for diabetes -- Gene therapy for cystic fibrosis lung disease -- Gene therapy of multiple sclerosis -- Gene therapy for myositis -- Gene therapy for osteoarthritis -- Gene therapy: Sjögren’s syndrome -- Disease mechanisms, genetic susceptibility and therapeutic approaches in lupus disease -- Regulated promoters -- Development of AAV vectors for the therapy of autoimmune and inflammatory diseases -- Delivery and application of plasmid DNA in arthritis gene therapy -- Helper-dependent adenoviral vectors -- Cells as carriers of gene therapy -- Perspectives for the future developments of gene therapy for autoimmune and inflammatory therapy.

This book addresses the latest advances in viral and non-viral vectors, novel targets and methods for the treatment of autoimmune and inflammatory disease with a main focus in pre-clinical testing with up to date clinical trials. The first section of the book deals with current research approaches for treating rheumatoid arthritis, osteoarthritis, diabetes, Crohn's disease, multiple sclerosis, Sjögrens syndrome, cystic fibrosis, myositis and lupus. The second section is devoted to cell delivery and vector development including plasmids, regulated promoters, adenovirus gutted vectors and adeno-associated vectors. All chapters are summarised by leaders in these fields. A must read for post graduate students, clinical and non-clinical researchers in the disciplines of immunology, molecular medicine, pharmacology, gene and cell-mediated therapy.